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Results for “Canadian Journal of Physiology and Pharmacology”

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2 recordsLinked to original sources
USGS1981

Effects of crude oil ingestion on avian intestinal function

Intestinal function in mallard ducklings ( Anas platyrhynchos ) on a freshwater regime was studied after a 7-day dietary ingestion of 0.25% and 2.5% Prudhoe Bay crude oil (PBCO) or a 2.5% paraffin mixture with an in vivo luminal perfusion technique. Dietary ingestion of 2.5% PBCO may have an effect on the integrity of the duckling intestine. There were no significant effects of PBCO on the absorption of Na, Cl, K, or H 2 O compared with control animals. The ducklings fed 2.5% paraffin had a significant depression in Na and H 2 O absorption compared with controls. However, this depression does not seem to be related to an effect on intestinal mucosa Na-K-ATPase activity.

Canadian Journal of Physiology and Pharmacology↗
USGS1984

Methyl parathion and fenvalerate toxicity in American kestrels: Acute physiological responses and effects of cold

Physiological and toxicological effects of p.o. methyl parathion (0.375-3.0 mg/kg) or fenvalerate (1000-4000 mg/kg) were examined over a 10-h period in American kestrels (Falco sparverius) maintained in thermoneutral (22?C) and cold (-5?C) environments. Methyl parathion was highly toxic (estimated median lethal dose of 3.08 mg/kg, 95% confidence limits of 2.29 -4.14 mg/kg), producing dose-dependent inhibition of brain and plasma cholinesterase activity, hyperglycemia, and elevated plasma corticosterone concentration. Brain and plasma cholinesterase inhibition in excess of 50% was associated with transient but pronounced hypothermia 2 h after intubation, although the magnitude of this response was yariable. Fenvalerate, at doses far exceeding those encountered in the environment, caused mild intoxication and elevated plasma alanine aminotransferase activity. Cold intensified methyl parathion toxicity, but did not affect that of fenvalerate. Thus, it would appear that organophosphorus insecticides pose far greater hazard than pyrethroids to raptorial birds.

Canadian Journal of Physiology and Pharmacology↗