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Handbook of ecotoxicology, second edition

Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. This authoritative work is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

Book

Elk monitoring in Mount Rainier and Olympic national parks: 2008-2011 synthesis report

In 2008, the USGS collaborated with the NPS, the Muckleshoot and Puyallup Indian Tribes, and WDFW to develop a protocol tor monitor changes in abundance, population composition, and spatial distribution of elk on summer ranges in MORA and OLYM and winter ranges in OLYM. We developed double-observer sightability (DO-S) models that adjusted raw counts of elk as a function of factors influencing detection probabilities from the air, e.g. vegetation, elk group size, light, elk activity, and pilot experience. We plan to develop DO-S models for both MORA and OLYM summer ranges, but due to radiotelemetry collar failures in OLYM, we do not yet have enough data to model detection probabilities in OLYM. We analyzed results of the first 4 years of elk monitoring conducted under the new protocol from 2008-2011. Objectives of this first synthetic analysis are to: • update the DO-S model for MORA aerial survey results • examine abundance, composition, and distribution of elk trends in MORA summer ranges • establish a baseline of counts, population composition, and distribution of elk in OLYM summer ranges • examine trends in counts and distribution of elk in OLYM low-elevation winter ranges during early spring • determine environmental factors influencing abundance and composition of elk in selected MORA summer ranges and unadjusted counts of elk on selected OLYM winter ranges • review progress in developing a DO-S model for OLYM elk surveys • examine aerial survey operations and provide suggestions for future surveys. There was no trend in elk numbers in the N. Rainier TCA from 2008-2011; the trend in the S. Rainier TCA was not statistically significant but increased 3.3%/year. Maximum counts increased in the N. Rainier TCA ~6%/year. Maximum counts in the S. Rainier TCA increased at a rate of 17% annually. Due to failed radiocollars, weather, and other problems, we completed surveys in 2 of 5 OLYM summer range TCAs; no trend data are available. In OLYM winter ranges, we surveyed the Hoh TCA during early spring 2008-10 and of the S. Fork Hoh and Queets in 2008 and 2010. No surveys were done for early-spring counts in 2011 and 2012 due to high snowfall and lack of funding. Legacy early-spring surveys in OLYM since 1985 allowed us to assess trends in counts in the early-spring TCAs from 1985-2010. Counts of elk in the early-spring TCAs declined: 63% in the S. Fork Hoh, 18% in the Hoh, and 22% in the Queets Valley. We continue to develop and improve the DO-S model for application to OLYM summer surveys. In the next synthesis report, we will update findings with additional data following the 2015 field season, based on 8 years of survey results; it will be a more complete analysis of elk population trends.

Washington

Assessment of selenium effects in lotic ecosystems

The selenium literature has grown substantially in recent years to encompass new information in a variety of areas. Correspondingly, several different approaches to establishing a new water quality criterion for selenium have been proposed since establishment of the national water quality criterion in 1987. Diverging viewpoints and interpretations of the selenium literature have lead to opposing perspectives on issues such as establishing a national criterion based on a sediment-based model, using hydrologic units to set criteria for stream reaches, and applying lentic-derived effects to lotic environments. This Commentary presents information on the lotic verse lentic controversy. Recently, an article was published that concluded that no adverse effects were occurring in a cutthroat trout population in a coldwater river with elevated selenium concentrations (C. J. Kennedy, L. E. McDonald, R. Loveridge, and M. M. Strosher, 2000, Arch. Environ. Contam. Toxicol. 39, 46–52). This article has added to the controversy rather than provided further insight into selenium toxicology. Information, or rather missing information, in the article has been critically reviewed and problems in the interpretations are discussed.

Ecotoxicology and Environmental Safety

Timing and origin for sand dunes in the Green River Lowland of Illinois, upper Mississippi River Valley, USA

The recent increase in dune studies in North America has been heavily focused in the Great Plains, while less attention has historically been given to the dune fields east of the Mississippi River. Here we report ages and suggest a potential sediment source for sand dunes in the Green River Lowland, Illinois, which may provide a better understanding of the dynamic interactions between eolian, glacial, lacustrine and fluvial processes that shaped the landscapes of the upper Midwest. Seven coherent optically stimulated luminescence ages (OSL, or optical ages) obtained from four sites suggest that major dune construction in the Green River Lowland occurred within a narrow time window around 17,500 ago. This implies either an enhanced aridity or an episodic increase of sediment supply at 17,500 years ago, or combination of the both. Contrary to previous assertions that dune sand was sourced from the deflation of the underlying outwash sand deposited when the Lake Michigan Lobe retreated from the area, we propose that Green River Lowland dunes sand originated from the Green Bay Lobe through the Rock River. Specifically, sediment supply increased in the Rock River valley during drainage of Glacial Lake Scuppernong, which formed between ???18,000 and 17,000 years ago, when the Green Bay Lobe retreated from its terminal moraine. The lake drained catastrophically through the Rock River valley, providing glacial sediment and water to erode the preexisting sandy sediments. Throughout the remainder of the late Pleistocene, the Laurentide Ice Sheet drained into larger more northerly glacial lakes that in turn drained through other river valleys. Therefore, the dunes in the Green River Lowland formed only during the catastrophic drainage of Glacial Lake Scuppernong, but were stabilized through the remainder of the Pleistocene. This scenario explains the abrupt dune construction around 17,500 years ago, and explains the lack of later dune activity up to the Pleistocene-Holocene transition. OSL and radiocarbon ages also indicate that dunes were reactivated during the early, middle and late Holocene. Some eolian activation occurred within well-defined dry intervals in the upper Midwest, suggesting that increased aridity may have been the primary driver in mobilizing sand. However, many ages do not correspond to drier periods. In contrast to the relative coherency of the Pleistocene OSL ages from multiple study sites, the Holocene OSL ages do not overlap from one site to another, suggesting that increased aridity alone cannot explain the multiple phases of dune reactivation in the Holocene. Therefore, we conclude that the combined effect of localized disturbances and greater aridity acted in concert to increase eolian sand activity in the Holocene. The multiple periods of eolian activity during the Holocene suggest a high potential for future sand activation in the region, and these results are informative for environmental prediction and potential future mitigation.

Quaternary Science Reviews

Reproductive outcomes in colonial fish-eating birds: A biomarker for developmental toxicants in Great Lakes food chains: I. Historical and ecotoxicological perspectives

Colonial fish-eating birds have been used as convenient model populations in which to study the impact of chronic exposure to complex mixtures of persistent lipophilic environmental contaminants within the Great Lakes ecosystem. To date, published reports of contaminant-induced adverse reproductive outcomes exist for six species. We briefly review the studies of the herring gull ( Larus argentatu s), Forster's tern ( Sterna forsteri ), and the double-crested cormorant ( Phalacrocorax auritus ) to illustrate the use of reproductive outcomes in fish-eating birds as a biomarkerfor developmental toxicants in Great Lakes food chains. We discuss the management implications of using various species for such purposes. We recommend that cormorants be used more extensively in biomonitoring programs to measure exposure and effects of polyhalogenated aromatic hydrocarbons and other contaminants in aquatic food chains in the Great Lakes.

Great Lakes

United States Geological Survey Yearbook, fiscal year 1977

Fiscal 1977 marked the 98th year the U.S. Geological Survey has endeavored in the unceasing task of providing information about the Earth and its physical resources, and regulating the activities of lessees engaged in extracting petroleum and other minerals from the public domain. The past year also marked the beginning of a third and challenging mission, drawing upon the Survey's scientific talents, to explore and assess the petroleum potential of a vast 37,000 square miles expanse of Alaska's North Slope known as the National Petroleum Reserve in Alaska. The first two missions require detailed and continuing investigations of the location, character, and extent of the Nation's land, water, mineral, and energy resources; a continuing National Topographic Mapping Program; the classification of Federal lands for mineral and waterpower potential; and a continuing program of technical review, safety inspection and royalty auditing of the operations of private parties engaged in mineral development on Federal lands to assure standards of safety, environmental protection, resource conservation, and a fair market return to the public for the development of their resources.

Yearbook

Cadmium risks to freshwater life: derivation and validation of low-effect criteria values using laboratory and field studies

In 2001, the U.S. Environmental Protection Agency (EPA) released updated aquatic life criteria for cadmium. Since then, additional data on the effects of cadmium to aquatic life have become available from studies supported by the EPA, Idaho Department of Environmental Quality (IDEQ), and the U.S. Geological Survey, among other sources. Updated data on the effects of cadmium to aquatic life were compiled and reviewed and low-effect concentrations were estimated. Low-effect values were calculated using EPA's guidelines for deriving numerical national water-quality criteria for the protection of aquatic organisms and their uses. Data on the short-term (acute) effects of cadmium on North American freshwater species that were suitable for criteria derivation were located for 69 species representing 57 genera and 33 families. For longer-term (chronic) effects of cadmium on North American freshwater species, suitable data were located for 28 species representing 21 genera and 17 families. Both the acute and chronic toxicity of cadmium were dependent on the hardness of the test water. Hardness-toxicity regressions were developed for both acute and chronic datasets so that effects data from different tests could be adjusted to a common water hardness. Hardness-adjusted effects values were pooled to obtain species and genus mean acute and chronic values, which then were ranked by their sensitivity to cadmium. The four most sensitive genera to acute exposures were, in order of increasing cadmium resistance, Oncorhynchus (Pacific trout and salmon), Salvelinus ('char' trout), Salmo (Atlantic trout and salmon), and Cottus (sculpin). The four most sensitive genera to chronic exposures were Hyalella (amphipod), Cottus, Gammarus (amphipod), and Salvelinus. Using the updated datasets, hardness dependent criteria equations were calculated for acute and chronic exposures to cadmium. At a hardness of 50 mg/L as calcium carbonate, the criterion maximum concentration (CMC, or 'acute' criterion) was calculated as 0.75 mug/L cadmium using the hardness-dependent equation CMC = e(0.8403 ? ln(hardness)-3.572) where the 'ln hardness' is the natural logarithm of the water hardness. Likewise, the criterion continuous concentration (CCC, or 'chronic' criterion) was calculated as 0.37 mug/L cadmium using the hardness-dependent equation CCC = (e(0.6247 ? ln(hardness)-3.384)) ? (1.101672 - ((ln hardness) ? 0.041838))). Using data that were independent of those used to derive the criteria, the criteria concentrations were evaluated to estimate whether adverse effects were expected to the biological integrity of natural waters or to selected species listed as threatened or endangered. One species was identified that would not be fully protected by the derived CCC, the amphipod Hyalella azteca. Exposure to CCC conditions likely would lead to population decreases in Hyalella azteca, the food web consequences of which probably would be slight if macroinvertebrate communities were otherwise diverse. Some data also suggested adverse behavioral changes are possible in fish following long-term exposures to low levels of cadmium, particularly in char (genus Salvelinus). Although ambiguous, these data indicate a need to periodically review the literature on behavioral changes in fish following metals exposure as more information becomes available. Most data reviewed indicated that criteria conditions were unlikely to contribute to overt adverse effects to either biological integrity or listed species. If elevated cadmium concentrations that approach the chronic criterion values occur in ambient waters, careful biological monitoring of invertebrate and fish assemblages would be prudent to validate the prediction that the assemblages would not be adversely affected by cadmium at criterion concentrations.

Scientific Investigations Report

Uncertainty of groundwater vulnerability assessments for agricultural regions in Hawaii: Review

There are important challenges associated with assessing potential groundwater vulnerability hazards that may result from regional scale applications of agrochemicals. The increasing availability of Geographic Information System (GIS) software to those involved in assisting with landuse decisions has resulted in the widespread production of multicolored risk management maps for many environmentally sensitive issues. Soil-based GIS's have recently been coupled to various solute-leaching models to make near-surface groundwater vulnerability assessments for guidance in pesticide regulation in several states. In general, these assessments rest on soil, climatic, and chemical data that are extremely sparse and contain considerable uncertainty. It is also important to acknowledge the uncertainty associated with the transport/fate processes that are not accounted for by the modeling approach used to make the assessment. In this paper, we review the results from a series of papers that have focused on characterization of uncertainty in pesticide mobility estimates, using the attenuation and retardation indices (AF and RF), for the Pearl Harbor Basin on the Hawaiian island of Oahu. Relative to data error uncertainties, we discuss the impacts of: (i) soil, climatic, and chemical data base uncertainties, (ii) reductions in data base uncertainties, (iii) extrapolation of soil data base information based on soil taxonomy and soil survey, and (iv) importing information from outside the region of interest. Relative to model error uncertainties, we compare pesticide leaching estimates from the simple AF and RF mobility indices with simulations from the EPA's Pesticide Root Zone Model (PRZM) and field observations. Finally, we outline a Regional Integrated Risk Assessment approach for characterizing regional scale groundwater vulnerability for near-surface nonpoint sources.

Hawaii

Review of Trace-Element Field-Blank Data Collected for the California Groundwater Ambient Monitoring and Assessment (GAMA) Program, May 2004-January 2008

Trace-element quality-control samples (for example, source-solution blanks, field blanks, and field replicates) were collected as part of a statewide investigation of groundwater quality in California, known as the Priority Basins Project of the Groundwater Ambient Monitoring and Assessment (GAMA) Program. The GAMA Priority Basins Project is being conducted by the U.S. Geological Survey (USGS) in cooperation with the California State Water Resources Control Board (SWRCB) to assess and monitor the quality of groundwater resources used for drinking-water supply and to improve public knowledge of groundwater quality in California. Trace-element field blanks were collected to evaluate potential bias in the corresponding environmental data. Bias in the environmental data could result from contamination in the field during sample collection, from the groundwater coming into contact with contaminants on equipment surfaces or from other sources, or from processing, shipping, or analyzing the samples. Bias affects the interpretation of environmental data, particularly if any constituents are present solely as a result of extrinsic contamination that would have otherwise been absent from the groundwater that was sampled. Field blanks were collected, analyzed, and reviewed to identify and quantify extrinsic contamination bias. Data derived from source-solution blanks and laboratory quality-control samples also were considered in evaluating potential contamination bias. Eighty-six field-blank samples collected from May 2004 to January 2008 were analyzed for the concentrations of 25 trace elements. Results from these field blanks were used to interpret the data for the 816 samples of untreated groundwater collected over the same period. Constituents analyzed were aluminum (Al), antimony (Sb), arsenic (As), barium (Ba), beryllium (Be), boron (B), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), iron (Fe), lead (Pb), lithium (Li), manganese (Mn), mercury (Hg), molybdenum (Mo), nickel (Ni), selenium (Se), silver (Ag), strontium (Sr), thallium (Tl), tungsten (W), uranium (U), vanadium (V), and zinc (Zn). The detection frequency and the 90th percentile concentration at greater than 90 percent confidence were determined from the field-blank data for each trace element, and these results were compared to each constituent's long-term method detection level (LT-MDL) to determine whether a study reporting level (SRL) was necessary to ensure that no more than 10 percent of the detections in groundwater samples could be attributed solely to contamination bias. Only two of the trace elements analyzed, Li and Se, had zero detections in the 86 field blanks. Ten other trace elements (Sb, As, Be, B, Cd, Co, Mo, Ag, Tl, and U) were detected in fewer than 5 percent of the field blanks. The field-blank results for these constituents did not necessitate establishing SRLs. Of the 13 constituents that were detected in more than 5 percent of the field blanks, six (Al, Ba, Cr, Mn, Hg, and V) had field-blank results that indicated a need for SRLs that were at or below the highest laboratory reporting levels (LRL) used during the sampling period; these SRLs were needed for concentrations between the LT-MDLs and LRLs. The other seven constituents with detection frequencies above 5 percent (Cu, Fe, Pb, Ni, Sr, W, and Zn) had field-blank results that necessitated SRLs greater than the highest LRLs used during the study period. SRLs for these seven constituents, each set at the 90th percentile of their concentrations in the field blanks, were at least an order of magnitude below the regulatory thresholds established for drinking water for health or aesthetic purposes; therefore, reporting values below the SRLs as less than or equal to (=) the measured value would not prevent the identification of values greater than the drinking-water thresholds. The SRLs and drinking-water thresholds, respectively, for these 7 trace elements are Cu (1.7 ?g/L and 1,300

Scientific Investigations Report

Factors influencing riverine fish assemblages in Massachusetts

The U.S. Geological Survey, in cooperation with the Massachusetts Department of Conservation and Recreation, Massachusetts Department of Environmental Protection, and the Massachusetts Department of Fish and Game, conducted an investigation of fish assemblages in small- to medium-sized Massachusetts streams. The objective of this study was to determine relations between fish-assemblage characteristics and anthropogenic factors, including impervious cover and estimated flow alteration, relative to the effects of environmental factors, including physical-basin characteristics and land use. The results of this investigation supersede those of a preliminary analysis published in 2010. Fish data were obtained for 669 fish-sampling sites from the Massachusetts Division of Fisheries and Wildlife fish-community database. A review of the literature was used to select fish metrics - species richness, abundance of individual species, and abundances of species grouped on life history traits - responsive to flow alteration. The contributing areas to the fish-sampling sites were delineated and used with a geographic information system to determine a set of environmental and anthropogenic factors that were tested for use as explanatory variables in regression models. Reported and estimated withdrawals and return flows were used together with simulated unaltered streamflows to estimate altered streamflows and indicators of flow alteration for each fish-sampling site. Altered streamflows and indicators of flow alteration were calculated on the basis of methods developed in a previous U.S. Geological Survey study in which unaltered daily streamflows were simulated for a 44-year period (water years 1961-2004), and streamflow alterations were estimated by use of water-withdrawal and wastewater-return data previously reported to the State for the 2000-04 period and estimated domestic-well withdrawals and septic-system discharges. A variable selection process, conducted using principal components analysis and Spearman rank correlation, was used to select a set of 15 non-redundant environmental and anthropogenic factors to test for use as explanatory variables in the regression analyses. Twenty-one fish species were used in a multivariate analysis of fish-assemblage patterns. Results of nonmetric multidimensional scaling and hierarchical cluster analysis were used to group fish species into fluvial and macrohabitat generalist habitat-use classes. Two analytical techniques, quantile regression and generalized linear modeling, were applied to characterize the association between fish-response variables and environmental and anthropogenic explanatory variables. Quantile regression demonstrated that as percent impervious cover and an indicator of percent alteration of August median flow from groundwater withdrawals increase, the relative abundance and species richness of fluvial fish decrease. The quantile regression plots indicate that (1) as many as seven fluvial fish species are expected in streams with little flow alteration or impervious cover, (2) no more than four fluvial fish species are expected in streams where flow alterations from groundwater withdrawals exceed 50 percent of the August median flow or the percent area of impervious cover exceeds 15 percent, and (3) few fluvial fish remain at high rates of withdrawal (approaching 100 percent) or high rates of impervious cover (between 25 and 30 percent). Three generalized linear models (GLMs) were developed to quantify the response of fluvial fish to multiple environmental and anthropogenic variables. All variables in the GLM equations were demonstrated to be significant (p less than 0.05, with most less than 0.01). Variables in the fluvial-fish relative-abundance model were channel slope, estimated percent alteration of August median flow from groundwater withdrawals, percent wetland in a 240-meter buffer strip, and percent impervious cover. Variables in the fluvial-fish species-richness model were drainage area, channel slope, total undammed reach length, percent wetland in a 240-meter buffer strip, and percent impervious cover. Variables in the brook trout relativeabundance model were drainage area, percent open water, and percent impervious cover. The variability explained by the GLM models, as measured by the pseudo R2, ranged from 18.2 to 34.6, and correlations between observed and predicted values ranged from 0.50 to 0.60. Results of GLM models indicated that, keeping all other variables the same, a one-unit (1 percent) increase in the percent depletion of August median flow would result in a 0.9-percent decrease in the relative abundance (in counts per hour) of fluvial fish. The results of GLM models also indicated that a unit increase in impervious cover (1 percent) resulted in a 3.7-percent decrease in the relative abundance of fluvial fish, a 5.4-percent decrease in fluvial-fish species richness, and an 8.7-percent decrease in brook trout relative abundance.

Massachusetts

Understanding behavioral responses of fish to pheromones in natural freshwater environments

There is an abundance of experimental studies and reviews that describe odorant-mediated behaviors of fish in laboratory microcosms, but research in natural field conditions has received considerably less attention. Fish pheromone studies in laboratory settings can be highly productive and allow for controlled experimental designs; however, laboratory tanks and flumes often cannot replicate all the physical, physiological and social contexts associated with natural environments. Field experiments can be a critical step in affirming and enhancing understanding of laboratory discoveries and often implicate the ecological significance of pheromones employed by fishes. When findings from laboratory experiments have been further tested in field environments, often different and sometimes contradictory conclusions are found. Examples include studies of sea lamprey (Petromyzon marinus) mating pheromones and fish alarm substances. Here, we review field research conducted on fish pheromones and alarm substances, highlighting the following topics: (1) contradictory results obtained in laboratory and field experiments, (2) how environmental context and physiological status influences behavior, (3) challenges and constraints of aquatic field research and (4) innovative techniques and experimental designs that advance understanding of fish chemical ecology through field research.

Journal of Comparative Physiology A

Ecological models supporting environmental decision making: A strategy for the future

Ecological models are important for environmental decision support because they allow the consequences of alternative policies and management scenarios to be explored. However, current modeling practice is unsatisfactory. A literature review shows that the elements of good modeling practice have long been identified but are widely ignored. The reasons for this might include lack of involvement of decision makers, lack of incentives for modelers to follow good practice, and the use of inconsistent terminologies. As a strategy for the future, we propose a standard format for documenting models and their analyses: transparent and comprehensive ecological modeling (TRACE) documentation. This standard format will disclose all parts of the modeling process to scrutiny and make modeling itself more efficient and coherent.

Trends in Ecology and Evolution

Balancing the scales: Including under-represented herptile species in a One Health approach

The One Health High-Level Expert Panel’s definition of One Health includes optimizing the health of people, animals (wild and domestic) and ecosystems. For many One Health practitioners, wildlife that can spread zoonoses are the focus, particularly if they can come in contact with people. However, ecosystem health is often best-indicated by less-encountered species, for instance, amphibians and reptiles. This review highlights how these taxa can benefit human health and well-being, including cultural significance, as well as their impact on plant, animal and environmental health. We highlight current challenges to the health of these species and the need to include them in the One Health Joint Action Plan. We conclude with a call to action for inclusion of amphibians and reptiles in a One Health approach.

Research Directions: One Health

Formation of the Isthmus of Panama

The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago (Ma), a result that if true would revolutionize our understanding of environmental, ecological, and evolutionary change across the Americas. To bring clarity to the question of when the Isthmus of Panama formed, we provide an exhaustive review and reanalysis of geological, paleontological, and molecular records. These independent lines of evidence converge upon a cohesive narrative of gradually emerging land and constricting seaways, with formation of the Isthmus of Panama sensu stricto around 2.8 Ma. The evidence used to support an older isthmus is inconclusive, and we caution against the uncritical acceptance of an isthmus before the Pliocene.

Science Advances

Tadpoles: the Biology of Anuran Larvae

The recent alarming declines in amphibian populations worldwide and the suitability of amphibians for use in answering research questions in disciplines as diverse as molecular systematics, animal behavior, ecology, and evolutionary biology have focused enormous attention on tadpoles. Yet despite this growing interest, relatively little is known about these fascinating creatures. n this invaluable reference, leading experts on tadpole biology relate what we currently know about tadpoles and what we might learn from them in the future. Tadpoles provides detailed summaries of tadpole morphology, development, behavior, ecology, and environmental physiology; explores the evolutionary consequences of the tadpole stage; synthesizes available information on their biodiversity, and presents a standardized terminology and an exhaustive literature review of tadpole biology.

Book

Environmental contaminants

The purpose of this chapter is to provide an overview of the ecotoxicology of major classes of environmental contaminants, with respect to sources, environmental chemistry, most likely routes of exposure, potential bioaccumulation and biomagification, mechanisms of toxicity, and effects on potentially vulnerable species of mammalian wildlife. Major contaminants reviewed were selected on the basis of their use patterns, availability and potential toxicity to wild mammals. These included pesticides used in agroecosystems (organochlorines, organophosphorus and carbamate compounds, anticoagulants, herbicides and fungicides), various organic pollutants (chlorobenzenes, chlorophenols, polychlorinated biphenyls, dibenzodioxins and dibenzofurans, and polycyclic aromatic hydrocarbons), heavy metals (lead, mercury, and cadmium), agricultural drainwater mixtures, leachates and radionuclides. Many of the above aspects of ecotoxicology and contaminants will be expanded upon in subsequent chapters of this book as they relate to distinct mammalian species and potential risk.

Book chapter

Freshwater neurotoxins and concerns for human, animal, and ecosystemhealth: A review of anatoxin-a and saxitoxin

Toxic cyanobacteria are a concern worldwide because they can adversely affect humans, animals, and ecosystems. However, neurotoxins produced by freshwater cyanobacteria are understudied relative to microcystin. Thus, the objective of this critical review was to provide a comprehensive examination of the modes of action, production, fate, and occurrence of the freshwater neurotoxins anatoxin-a and saxitoxin as they relate to human, animal, and ecosystem health. Literature on freshwater anatoxin-a and saxitoxin was obtained and reviewed for both laboratory and field studies. Current (2020) research identifies as many as 41 anatoxin-a producing species and 15 saxitoxin-producing species of freshwater cyanobacteria. Field studies indicate that anatoxin-a and saxitoxin have widespread distribution, and examples are given from every continent except Antarctica. Human and animal health concerns can range from acute to chronic. However, few researchers studied chronic or sublethal effects of freshwater exposures to anatoxin-a or saxitoxin. Ecosystemhealth also is a concern, as the effects of toxicity may be far reaching and include consequences throughout the food web. Several gaps in knowledgewere identified for anatoxin-a and saxitoxin, including triggers of production and release, environmental fate and degradation, primary and secondary exposure routes, diel variation, food web effects, effects of cyanotoxin mixtures, and sublethal health effects on individual organisms and populations. Despite the gaps, this critical review facilitates our current understanding of freshwater neurotoxins and thus can serve to guide future research on anatoxin-a, saxitoxin, and other cyanotoxins.

Science of the Total Environment